Chronic Fatigue Syndrome Complete Practice Test 2026

Chronic Fatigue Syndrome (CFS) is frequently associated with depression due to several factors. CFS is characterized by persistent fatigue that does not improve with rest and can significantly impact an individual’s daily functioning and quality of life. This constant fatigue often leads to social isolation, frustration, and a sense of loss, which can contribute to the development of depressive symptoms.

Moreover, the overlapping symptoms between CFS and depression, such as sleep disturbances, cognitive difficulties, and emotional distress, further complicate the clinical picture. Individuals with CFS may also experience a persistent low mood or lack of interest in activities, which are hallmark signs of depression.

While anxiety and insomnia are also commonly experienced by individuals with CFS, the stronger connection and prevalence of depression as a co-occurring condition make it the most recognized association in clinical settings. Osteoporosis, while a significant health issue in other contexts, does not have a direct link to CFS and is generally considered unrelated to the syndrome's primary symptoms.